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CME Credit Offered
CME Credit Offered
Abstract Award
Abstract Award
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Poster Session 3

(941) Race, ethnicity, and outcomes in pregnancies with gestational diabetes: a secondary analysis of nuMoM2b dataset

Friday, January 31, 2025
10:30 AM – 12:30 PM  

    Submitting Author and Presenting Author(s)

  • Xiang Yu Feng, MD (she/her/hers)

    MFM Fellow
    University of California, Irvine Division of Maternal-Fetal Medicine
    University of California, Irvine, California, United States

    • Coauthor(s)

  • JC

    Jenny Chang, MS

    University of California Irvine
    Orange, California, United States

  • AZ

    Argyrios Ziogas, PhD

    University of California Irvine
    Orange, California, United States

  • Rebecca J. Post, MD (she/her/hers)

    Maternal Fetal Medicine Physician
    University of California Irvine
    Orange, California, United States

  • Judith H. Chung, MD

    Professor of Clinical Obstetrics and Gynecology
    University of California- Irvine
    Irvine, California, United States

Objective: Studies have demonstrated higher rates of gestational diabetes in racial and ethnic minorities. Management of gestational diabetes requires various dietary and lifestyle changes in pregnancy. This study evaluates the association between race, ethnicity, specific risk factors and outcomes in nulliparous pregnancies affected by gestational diabetes.

Study Design: This study is a secondary analysis of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b), a prospective cohort study following nulliparas throughout pregnancy. Patients diagnosed with gestational diabetes were analyzed by racial/ethnic groups. Primary outcome was neonatal hypoglycemia. Secondary outcomes were selected neonatal and maternal morbidities. ANOVA test and Fisher’s exact were used for analysis of difference in race/ethnicity group. Multivariate logistic regression was used to adjust for confounders.

Results: Of the cohort of 10,037 patients, 396 were diagnosed with gestational diabetes, with 54.5% patients identifying as non-Hispanic White, 10.4% non-Hispanic Black, 18.7% Hispanic, and 16.4% all other. Variance by race/ethnicity was found for multiple characteristics such as age, body mass index, dietary caloric and carbohydrate intake, chronic hypertension, socioeconomic status, health literacy, and experience of racism (all p values < 0.047). After adjusting for these potential confounders, rates of neonatal hypoglycemic were not statistically significant. However, rate for cesarean was higher for non-Hispanic Black p</span>atients (aOR 2.18, 95% CI 1.02-4.70) and macrosomia higher for Hispanic patients (aOR 2.98, 95% CI 1.10-8.09).

Conclusion: Variance was observed in racial/ethnic groups for multiple characteristics including dietary caloric intake and carbohydrate intake in patients with gestational diabetes. Although odds of neonatal hypoglycemia were not significant between groups, differences in cesarean delivery and macrosomia rates were seen. These findings may impact developing culturally individualized care in counseling and management of gestational diabetes.