Director MFM
The Ohio State University
Dr. Costantine is the Frederick P. Zuspan Professor of Obstetrics and Gynecology and Division Director of Maternal Fetal Medicine at the Ohio State University Wexner Medical Center. He graduated from the American University of Beirut, completed his residency in OB/GYN at the University of Cincinnati, and fellowship in Maternal Fetal Medicine at the University of Texas Medical Branch, Galveston, TX.
Dr. Costantine is an active clinical investigator, having published over 220 scholarly articles and book chapters. His primary research interests are hypertensive disorders of pregnancy, perinatal pharmacology, preterm birth, and repurposing medications for the prevention of pregnancy morbidities focusing on the role of statins in prevention of preeclampsia. He is currently the Principal Investigator for OSU’s participation in the NICHD Maternal Fetal Medicine Units Network, PCORI funded comparative effectiveness of different doses of aspirin for prevention of hypertensive disorders of pregnancy, and the NICHD funded MPRINT Translational Resource Platform for monitoring therapeutics in pregnancy. Additionally, he is the PI or site PI on numerous multicenter federal and industry sponsored trials in pregnancy. At Ohio State, Dr. Costantine oversees the clinical, research, and administrative operations of the division of Maternal Fetal Medicine. Additionally, he is an associate editor for American Journal of Perinatology, reviewer for national and international societies and institutes, and serves on various NIH Scientific Review Groups.